Status:
UNKNOWN
Clinical and Radiographic Evaluation of Guided Tissue Regeneration With Radiation-sterilized Allogenic Bone Grafts or Xenogenic Grafts for the Treatment of Intrabony Defects in Aggressive Periodontitis
Lead Sponsor:
Medical University of Warsaw
Conditions:
Periodontitis, Aggressive
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
The treatment of intrabony defects in patients with aggressive periodontitis remains a challenging procedure and novel therapeutic strategies are sought. The purpose of this study is to compare the cl...
Eligibility Criteria
Inclusion
- Diagnosis of aggressive periodontitis in line with American Academy of Periodontology classification (Lang et al. 1999)
- Familial aggregation (history of periodontitis in parents or siblings)
- Presence of at least two teeth with probing pocket depth (PPD) ≥ 6mm and clinical attachment level (CAL) ≥ 5 mm associated with an intrabony defect of at least 3 mm as detected in diagnostic periapical radiographs
- No furcation involvement of the teeth presenting the intraosseous defects
- The width of keratinized tissue on the facial aspect of the selected teeth ≥ 2 mm
Exclusion
- Full-mouth plaque index ≥ 20% (Ainamo \& Bay 1975)
- Full-mouth sulcus bleeding index ≥ 15% (Mühlemann \& Son 1971)
- Smoking more than 10 cigarettes/day
- Systemic diseases with compromised healing potential of infectious diseases
- Drugs affecting periodontal health / healing
- Pregnant and lactating females
- Previous periodontal surgery in the area
Key Trial Info
Start Date :
January 5 2018
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 5 2019
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT03340012
Start Date
January 5 2018
End Date
May 5 2019
Last Update
November 13 2017
Active Locations (1)
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1
Department of Periodontology and Oral Mucosa Diseases, Medical University of Warsaw
Warsaw, Mazowsze, Poland, 00-246