Status:

UNKNOWN

The Effect of an Oral Supplement,TK3 (Tryptophan and Thiamine) on the Quality of Life and Chemotherapy Tolerance in Cancer Patients With Advanced Disease.

Lead Sponsor:

Faculdade de Medicina do ABC

Conditions:

Cancer

Quality of Life

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

The product under investigation relates to a pharmaceutical composition containing a pyrimidine nitrogen base, thymine, and the essential amino acid tryptophan. This product seems to have effect on qu...

Detailed Description

The primary objective of this study is to evaluate the impact of TK3 on the quality of life of patients receiving anti-neoplastic chemotherapy. The secondary objectives are to evaluate the influence o...

Eligibility Criteria

Inclusion

  • Patients who agree to study procedures and sign the informed consent
  • Patients 18 years of age or older;
  • Patients undergoing oncologic treatment for advanced neoplasms. It is understood by advanced patient disease patients with unresectable or with distant metastases.
  • Participants should present at least one (1) of the following clinical side effects that can be assessed according to CTCAE (Version 4.0): fatigue, nausea, vomiting, diarrhea, or mucositis.
  • Patients with programming to receive at least 3 cycles of anti-neoplastic chemotherapy;
  • Patients may be on radiotherapy

Exclusion

  • Use of vitamin complex or concomitant food supplement;
  • Current use or programming of parenteral diet use;
  • Hypersensitivity to the components of the formula;
  • Participation in another clinical study or use of any investigational product within 28 days prior to commencement of treatment in this clinical trial, unless the Investigator deems there to be a clinical benefit therefore;

Key Trial Info

Start Date :

November 1 2017

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 1 2019

Estimated Enrollment :

140 Patients enrolled

Trial Details

Trial ID

NCT03341286

Start Date

November 1 2017

End Date

May 1 2019

Last Update

November 14 2017

Active Locations (1)

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Faculdade de medicina do ABC-CEPHO

Santo André, São Paulo, Brazil, 09060-870