Status:
COMPLETED
Genes-in-Action - Hepcidin Regulation of Iron Supplementation
Lead Sponsor:
London School of Hygiene and Tropical Medicine
Collaborating Sponsors:
University of Oxford
Conditions:
Anemia
Eligibility:
All Genders
18+ years
Brief Summary
Anaemia continues to be one of the most common health problems affecting children and pregnant women in low-income countries. Nutritional iron deficiency is believed to be the main driver of anaemia, ...
Detailed Description
Anaemia is a recalcitrant problem in global health, affecting particularly children and childbearing women in sub-Saharan Africa. Anaemia causes impaired growth and cognitive development in children, ...
Eligibility Criteria
Inclusion
- Be healthy and over 18 years of age old.
- Have provided appropriate ethical consent for involvement in studies relating to genetics.
- Have available genotype data based on previous or ongoing genetic studies. Fasted (overnight)
Exclusion
- Indication of infection/inflammation at the time of enrollment as determined by self-reporting, medical history or hematology (full blood count)
- Severe anemia (HGB\<7 g/dL)
- Pregnant and lactating women
- Carrier of known genetic variants associated with iron metabolism (sickle trait, G6PD deficiency variants, HFE polymorphisms
Key Trial Info
Start Date :
September 5 2016
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 29 2019
Estimated Enrollment :
206 Patients enrolled
Trial Details
Trial ID
NCT03341338
Start Date
September 5 2016
End Date
April 29 2019
Last Update
August 14 2019
Active Locations (1)
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1
Keneba Field Station
Fajara, The Gambia