Status:
UNKNOWN
Serum Concentration of Wnt2 and Wnt4 in Patients With Acute Coronary Syndrome
Lead Sponsor:
The First Affiliated Hospital of Dalian Medical University
Collaborating Sponsors:
Fudan University
Conditions:
Acute Coronary Syndrome
Eligibility:
All Genders
40-80 years
Brief Summary
This study aims to find the change of serum wnt effectory moleculars and the association with Hs-CRP，cTnI and Prognosis in Patients with Acute Coronary Syndrome.
Detailed Description
It has been reported that wnt effecory moleculars (wnt2, wnt4, wnt11,wnt10b, DKK1, DKK2) increased in myocardium at acute phase after myocardium infarction in animal experiment. These moleculars can b...
Eligibility Criteria
Inclusion
- .diagnosed as acute coronary syndrome, including STEMI and NST-ACS.
- with left ventricular ejection fraction（LVEF）\>=45%
- written informed consents are obtained
- admitted within 24 hours after chest pain attacked
Exclusion
- • complicated with rheumatic heart disease, coronary arteritis, hypertrophic cardiomyopathy or dilated cardiomyopathy
- complicated with malignant tumor,the immune system diseases, blood system diseases, recently (within 2 weeks) taking glucocorticoid drugs, the use of immunosuppressive agents and cerebral infarction
- with acute or chronic infection, surgery or trauma in the last month
- secondary hypertension, severe liver dysfunction,severe renal insufficiency
- with abnormal thyroid function or allergy to iodine agent refusal to sign the informed consent
Key Trial Info
Start Date :
September 29 2017
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 29 2019
Estimated Enrollment :
450 Patients enrolled
Trial Details
Trial ID
NCT03342131
Start Date
September 29 2017
End Date
March 29 2019
Last Update
February 8 2018
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
The First Affiliated Hospital of Dalian Medical University
Dalian, Liaoning, China, 116011