Status:
COMPLETED
Glutamate Neuro-Excitotoxicity in GWI
Lead Sponsor:
American University
Collaborating Sponsors:
Georgetown University
United States Department of Defense
Conditions:
Gulf War Syndrome
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
The objective of the proposed research is to examine whether dietary exposure to food additives containing glutamate may be contributing to symptoms in Gulf War Illness (GWI). The rationale for propos...
Detailed Description
Objective/ Hypothesis: The objective of this clinical trial is to test the effectiveness of a low-glutamate diet in GWI patients, as a way to mediate symptom occurrence by reducing excess glutamatergi...
Eligibility Criteria
Inclusion
- Males \& Females
- Served (and was deployed) in the Persian Gulf War
- Fulfill both Kansas and CDC definitions of GWI
- Stable medication regimen for 3 or more months
Exclusion
- Active Duty Military
- Current substance use disorder
- Unwilling to change diet for 2 months
- Severe asthma requiring past hospitalization
- Seizure disorder
Key Trial Info
Start Date :
November 14 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 31 2020
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT03342482
Start Date
November 14 2017
End Date
August 31 2020
Last Update
January 12 2021
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
American University
Washington D.C., District of Columbia, United States, 20016