Status:
COMPLETED
Gait Adaptability: Tracking Locomotor Recovery After Incomplete Spinal Cord Injury
Lead Sponsor:
University of Zurich
Collaborating Sponsors:
Foundation Wings For Life
Conditions:
Gait Disorders, Neurologic
Gait Disorder, Sensorimotor
Eligibility:
All Genders
18-80 years
Brief Summary
Adaptive gait assessements will be evaluated as a potential new marker for tracking locomotor recovery throughout rehabilitation of spinal cord injury subjects. To this end, controls, subacute and chr...
Eligibility Criteria
Inclusion
- Informed Consent as documented by signature (Appendix Informed Consent Form)
- Healthy controls
- Patients with an incomplete spinal cord injury in a chronic (at least 12 months post-injury) or subacute (3-6 months post-injury) stage of recovery
- Age: 18 years and older
- Able to stand without physical assistance and handrails for more than 120s
- preserved segmental and cutaneo-muscular reflexes in the lower limbs
- Bodyweight over 20 kg and under 120 kg
- Mini-Mental state examination score 26 (test only performed if cognitive deficits are suspected)
Exclusion
- Current orthopedic problems
- Neurological impairment other than SCI
- Premorbid major depression or psychosis
- Metal implants in the cervical skull
- History of significant autonomic dysreflexia with treatment
- Dermatological issues (e.g. decubitus) at the harness attachment site (back, abdomen, upper legs)
- Malignant diseases
- Heart insufficiency NYHA III-IV
- Potential pregnancy
- Unlikely to complete the intervention or return for follow-up
- Participation in another training study
- Contraindications for training using the GRAIL (according the manual)
Key Trial Info
Start Date :
January 1 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 2 2022
Estimated Enrollment :
98 Patients enrolled
Trial Details
Trial ID
NCT03343132
Start Date
January 1 2018
End Date
September 2 2022
Last Update
September 7 2022
Active Locations (1)
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1
Universitätsklinik Balgrist
Zurich, Switzerland, 8008