Status:
RECRUITING
The Effects of Different Anesthetics on Functional Connectivity
Lead Sponsor:
Beijing Tiantan Hospital
Conditions:
Sedation
Eligibility:
MALE
18-65 years
Phase:
NA
Brief Summary
This research is a prospective cohort study. The aim of the study is to determine different levels of sedative mechanism and the effect on brain functional connectivity of midazolam, dexmedetomidine a...
Detailed Description
This research will include 120 healthy volunteers and 120 brain tumor patients; the participants will be allocated into midazolam, dexmedetomidine and propofol group. Resting and task fMRI will be per...
Eligibility Criteria
Inclusion
- 1\. Male, 18 \~ 65 years old
- 2\. Healthy Volunteer / Brain Tumor Patients
- 3\. Senior high school and above
- 4\. Sign informed consent
Exclusion
- 1\. In vivo implant MRI check taboo
- 2\. Cardiopulmonary liver and kidney and other systemic complications
- 3\. History of major surgical anesthesia
- 4\. Abuse of drugs, alcoholism history
- 5\. Test drug allergy history
- 6\. Claustrophobia
- 7\. Left hand
Key Trial Info
Start Date :
April 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
240 Patients enrolled
Trial Details
Trial ID
NCT03343873
Start Date
April 1 2017
End Date
December 31 2025
Last Update
August 1 2024
Active Locations (1)
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1
Beijing Tian Tan Hospital
Beijing, China, 100070