Status:

COMPLETED

Study of the Reversibility of Vigilance Dysfunction at 6 Months of Continuous Positive Airways Pressure (CPAP) in Patients With Obstructive Sleep Apnea/Hypopnea Syndrome (OSAHS)

Lead Sponsor:

Poitiers University Hospital

Conditions:

Vigilance Dysfunction

Eligibility:

All Genders

20-69 years

Phase:

NA

Brief Summary

It is a monocentric prospective pilot study in Poitiers University Hospital, specifically analyzing the vigilance disorders in the Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) and their reversibi...

Eligibility Criteria

Inclusion

  • Patients aged 20-70 years
  • Memory disorders without memory problems in episodic memory
  • Presence of polysomnography of a obstructive sleep apnea/hypopnea syndrome (OSAHS) requiring Continuous positive airways pressure
  • Moderate OSAHS (Apnea Hypopnea Index ≥ 15 / hour with arousals ≥ 10)
  • Severe OSAHS (Apnea Hypopnea Index ≥ 30 / h)

Exclusion

  • Age \<20 years or ≥ 70 years
  • Neurodegenerative disease (Alzheimer's disease, Parkinson's disease)
  • Dysthyroidism
  • Severe depression, schizophrenia, bipolar disorder
  • Treatment with an effect on cognition: hypnotics, sedative
  • Chronic Obstructive Pulmonary Disease
  • Chronic alcoholism, other addictions
  • Contraindications to Magnetic Resonance Imaging
  • Refusal of equipment

Key Trial Info

Start Date :

November 17 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 9 2021

Estimated Enrollment :

23 Patients enrolled

Trial Details

Trial ID

NCT03344263

Start Date

November 17 2017

End Date

February 9 2021

Last Update

November 29 2021

Active Locations (1)

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service de neurologie CHU DE POITIERS

Poitiers, France, 86000