Status:
UNKNOWN
Effect of Intraoperative IV Ketamine on Postoperative Morphine Consumption During Intestinal Surgery
Lead Sponsor:
Assiut University
Conditions:
Postoperative Analgesia
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
.The aim of this study is to identify the analgesic effect of intraoperative ketamine intravenous infusion on patients undergoing intestinal surgery and its effect on salivary cortisol and alpha amyla...
Detailed Description
I- Group K (ketamine): 30 patients will receive intraoperative intravenous ketamine infusion. II- Group C (control): 30 patients will receive intraoperative intravenous normal saline infusion.
Eligibility Criteria
Inclusion
- \- Patient's status ASA status-I and II.
- Patients age above 18 years old.
- Patients scheduled for intestinal surgery.
Exclusion
- Patient refusal.
- Patients with known allergy to ketamine or morphine.
- Patients with significant hepatic dysfunction.
- Patients with severe renal disease.
- Significant Heart disease.
- Patients with chronic pain.
- Regular use analgesics, antidepressants or opioids in last 2 months.
- Any known convulsive disorder.
- Morbid obesity (BMI\>35).
- Patients with autoimmune disease
- Patients on corticosteroid therapy
- Pregnancy.
- Breast feeding.
- Woman under hormonal treatment.
- Oral disease.
Key Trial Info
Start Date :
December 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2019
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT03344393
Start Date
December 1 2017
End Date
March 1 2019
Last Update
November 17 2017
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