Status:
UNKNOWN
PHysical Activity and Exercise Outcomes in Huntington's Disease
Lead Sponsor:
Cardiff University
Collaborating Sponsors:
CHDI Foundation, Inc.
Conditions:
Huntington Disease
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Huntington's disease (HD) is a genetic, degenerative neurological disease that affects individuals in their third-fourth decade of life and individuals can live 15-20 years with manifest HD. The compl...
Detailed Description
Huntington's disease (HD) is a neurodegenerative disease causing dysfunction and death of medium spiny striatal projection neurons and thus disruption of corticostriatal pathways with resultant impair...
Eligibility Criteria
Inclusion
- Diagnosis of HD, confirmed by genetic testing
- Above the age of 18
- A participant (current or newly enrolled) in the Enroll-HD study
- Up to and including stage 2 disease status (TFC 7-13)
Exclusion
- Diagnosis of juvenile onset HD
- History of co-morbid neurological conditions such as multiple sclerosis or stroke
- Acute orthopaedic conditions (within a month) e.g. ankle sprain or fracture
- Inability or unwillingness of participant or legal guardian to give written informed consent
Key Trial Info
Start Date :
February 16 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 31 2020
Estimated Enrollment :
116 Patients enrolled
Trial Details
Trial ID
NCT03344601
Start Date
February 16 2018
End Date
August 31 2020
Last Update
November 5 2019
Active Locations (6)
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1
Re+Active Therapy and Wellness Centre/ UCLA
Los Angeles, California, United States, 90045
2
Teacher's College, Columbia University
New York, New York, United States, 10027
3
George Huntington Institute
Münster, Germany, 48149
4
University Hospital Ulm
Ulm, Germany, 89081