Status:
UNKNOWN
Standard Versus Intensive Monitoring After Myocardial Infarction Looking for Atrial Fibrillation
Lead Sponsor:
University of British Columbia
Conditions:
Atrial Fibrillation New Onset
Myocardial Infarction
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
After a myocardial infarction (MI), patients discharged home in sinus rhythm may develop AF that is asymptomatic, undetected, and undertreated. Previous studies (CARISMA and ARREST) have demonstrate h...
Detailed Description
The SIMPL-AF trial will evaluate the role of intensive monitoring after myocardial infarction, assessing for new-onset AF after hospital discharge. Patients will be randomized to receive intensive mon...
Eligibility Criteria
Inclusion
- Patients with ST-elevation myocardial infarction (STEMI) or Non-ST-elevation myocardial infarction (NSTEMI; Third Universal Definition of MI) with or without PCI. All patients must have troponin elevation.
- No history of AF during hospitalization, at discharge, or pre-existing AF documented on history (i.e. hospital records, previous hospitalization, ECG records).
- No anticoagulation for AF or other indications (i.e. LV thrombus, heart valves, venous thromboembolism/deep venous thrombosis).
- No concomitant disease expected to reduce expected lifespan to \<2 yrs.
Exclusion
- Patients receiving CABG surgery during this hospitalization or planned cardiac surgery within the next 3 months.
- Patients with spontaneous coronary artery dissection (SCAD), non-atherosclerotic coronary disease (NACAD), and Takotsubo cardiomyopathy are excluded from this study.
- Patients with contraindications to anticoagulation.
- Patients with a chronic skin disorder on the upper torso, or an allergy to medical tape or glue.
Key Trial Info
Start Date :
November 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2022
Estimated Enrollment :
240 Patients enrolled
Trial Details
Trial ID
NCT03345615
Start Date
November 1 2017
End Date
December 1 2022
Last Update
August 16 2022
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Vancouver General Hospital
Vancouver, British Columbia, Canada, V5Z 1M9