Status:
COMPLETED
Outcomes of Adipose Derived Mesenchymal Stem Cells on Sexual Hormone Deficiency
Lead Sponsor:
Vinmec Research Institute of Stem Cell and Gene Technology
Conditions:
Hormone Deficiency
Eligibility:
All Genders
35-70 years
Phase:
PHASE1
PHASE2
Brief Summary
The purpose of this study is to evaluate the safety and effectiveness of adipose derived mesenchymal stem cells (AD-MSCs) therapy on sexual hormone deficiency in the middle-aged patients
Detailed Description
The purpose of this study is to evaluate the safety and efficiency of adipose-derived mesenchymal stem cells in 30 patients with sexual hormone deficiency at Vinmec International Hospital, Hanoi, Viet...
Eligibility Criteria
Inclusion
- Age: 35 years to 70 years (Male) and from 35 years to menopause age (Female)
- Male: decrease in libido, decrease in intercourse frequency, erectile dysfunction, Difficulty in concentration, testosterone level ≤ 12 nMol/dL
- Female: reduced or absent menstruation after radiation exposure or chemotherapy; Hot flushes, excessive sweating, and anxiety, together with other symptoms associated with the menopause, AMH level ≤ 2 ng/ml and/or FSH level ≥ 10 mIU/ml.
- Patients signed the informed consent form
Exclusion
- Surgery removal of endocrine glands
- Abnormalities in the endrocrine glands
- Hormone deficiency due to diabetes and other metabolic disorders
- Active autoimmune diseases
- Current usage of immunosuppressive drugs
- Coagulation disorders
- Allergy to anesthetic agents
- Severe health conditions such as cancer, failure of heart, lung, liver or kidney
- Active infections
Key Trial Info
Start Date :
November 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 30 2020
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT03346967
Start Date
November 1 2017
End Date
March 30 2020
Last Update
June 4 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Vinmec Research Institute of Stem Cell and Gene Technology
Hanoi, Vietnam, 10000