Status:

COMPLETED

A Study to Evaluate the Long-Term Safety and Efficacy of Bimekizumab in Subjects With Psoriatic Arthritis

Lead Sponsor:

UCB Biopharma SRL

Conditions:

Psoriatic Arthritis

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

This is a study to assess the long-term safety and tolerability of bimekizumab in subjects with psoriatic arthritis

Eligibility Criteria

Inclusion

  • In the opinion of the Investigator, the subject is expected to benefit from participation in an Open Label Extension (OLE) study
  • Subject completed PA0008 without meeting any withdrawal criteria
  • Female subjects must be postmenopausal, permanently sterilized or, if of childbearing potential, must be willing to use a highly effective method of contraception
  • Male subjects with a partner of childbearing potential must be willing to use a condom when sexually active

Exclusion

  • Female subjects who plan to become pregnant during the study or within 20 weeks following the last dose of IMP. Male subjects who are planning a partner pregnancy during the study or within 20 weeks following the last dose
  • Subjects with any current sign or symptom that may indicate a medically significant active infection (except for the common cold) or has had an infection requiring systemic antibiotics within 2 weeks of study entry
  • Subjects who meet any withdrawal criteria in PA0008. For any subject with an ongoing Serious Adverse Event, or a history of serious infections (including hospitalizations) in the lead-in study, the Medical Monitor must be consulted prior to the subject's entry into PA0009

Key Trial Info

Start Date :

November 22 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 29 2020

Estimated Enrollment :

184 Patients enrolled

Trial Details

Trial ID

NCT03347110

Start Date

November 22 2017

End Date

October 29 2020

Last Update

December 1 2023

Active Locations (37)

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Page 1 of 10 (37 locations)

1

Pa0009 025

Lexington, Kentucky, United States, 40504

2

Pa0009 003

Hagerstown, Maryland, United States, 21502

3

Pa0009 011

Lansing, Michigan, United States, 48910

4

Pa0009 028

Rochester, New York, United States, 14642

A Study to Evaluate the Long-Term Safety and Efficacy of Bimekizumab in Subjects With Psoriatic Arthritis | DecenTrialz