Status:
UNKNOWN
Deep Brain Stimulation of Nucleus Accumbens for Methamphetamine Addiction
Lead Sponsor:
Ruijin Hospital
Conditions:
Treatment Methamphetamine Addiction
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
The main objective of this study is to assess the efficacy of bilateral deep brain stimulation (DBS) of the Nucleus Accumbens(NAc) as a novel treatment in severe methamphetamine addiction. Our hypothe...
Eligibility Criteria
Inclusion
- DSM-IV-TR diagnosis of Drug addiction disorder;
- Age 18-65 years old;
- Proficiency in Mandarin language;
- Failure to detox more than three times;
- Capacity to provide informed consent (understanding of the study purpose and methods);
Exclusion
- Multidrug abuse and formation of addiction;
- Serious and unstable organic diseases (e.g. unstable coronal heart disease);
- Any history of seizure disorder or hemorrhagic stroke;
- Past stereotactic neurosurgical intervention;
- Neurological disease (Abnormal PET-CT, MRI, EEG)
- Contraindications of MRI-examination, e.g. implanted cardiac pacemaker/ heart defibrillator;
- Contraindications of stereotactic intervention, e.g. increased bleeding disposition, cerebrovascular diseases (e.g. arteriovenous malfunction, aneurysms, systemic vascular diseases);
- HIV positive;
- Pregnancy and/or lactation;
Key Trial Info
Start Date :
September 20 2017
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 30 2020
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT03347474
Start Date
September 20 2017
End Date
December 30 2020
Last Update
October 26 2018
Active Locations (1)
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1
Shanghai Ruijin Hospital Functional Neurosurgery
Shanghai, Shanghai Municipality, China, 200025