Status:
COMPLETED
Double-blind Placebo Surgery Trial for Treatment of Parkinson's Disease
Lead Sponsor:
University of Denver
Conditions:
Parkinson Disease
Surgery
Eligibility:
All Genders
30-75 years
Phase:
NA
Brief Summary
A double-blind sham surgery-controlled trial was developed to determine the effectiveness of implantation of human embryonic dopamine neurons into the putamen of patients with advanced Parkinson's dis...
Detailed Description
A double-blind sham surgery-controlled trial was conducted to determine the effectiveness of implantation of human embryonic dopamine neurons into the putamen of patients with advanced Parkinson's dis...
Eligibility Criteria
Inclusion
- Diagnosed with Parkinson's disease (PD) for more than 7 years, improvement in response to levodopa, Positive Emission Tomography scan compatible with presence of PD, improvement of at least 33% on UPDRS after first morning dose of levodopa
Exclusion
- Mini-mental status exam score of less than 24, hallucinations during levodopa therapy, epilepsy, previous brain surgery, severe depression, another neurologic disorder, cardiovascular disease, and medical contraindication of surgery
Key Trial Info
Start Date :
November 1 1994
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 1999
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT03347955
Start Date
November 1 1994
End Date
February 1 1999
Last Update
November 20 2017
Active Locations (1)
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1
Morgridge College of Education, University of Denver
Denver, Colorado, United States, 80208