Status:

UNKNOWN

Evaluation of the Predictors of Clinical and Radiological Response to Gamma-Knife Radiosurgery in the Treatment of Intermediate Ventral Nucleus of the Thalamus (VIM) Thalamotomy Tremor.

Lead Sponsor:

Assistance Publique Hopitaux De Marseille

Conditions:

Severe Disabling Tremor

Eligibility:

All Genders

20+ years

Brief Summary

Gamma-Knife radiosurgery of the VIM for patients presenting with severe drug-resistant tremor is now current practice as an alternative to Deep Brain Stimulation (DBS) of the VIM. Now, around 100 pat...

Eligibility Criteria

Inclusion

  • Male or female aged 20 years minimum
  • Patient with absolute contraindication or relative to deep brain stimulation (DBS) of VIM.
  • Patient having the Gamma Knife radiosurgery of VIM (combining clinical and paraclinical conditions).
  • Patient affiliated to a social security scheme.
  • Patient having understood and signed the information notice for non opposition.

Exclusion

  • Patient having a contraindication to performing a cerebral MRI (pace-maker, intracerebral metallic object etc.)
  • Patient with a contraindication to radiosurgical treatment (previous treatment with cerebral radiotherapy)
  • Vulnerable persons: minors, protected adults (guardianship or trusteeship) and adults unable to express their non-opposition.

Key Trial Info

Start Date :

October 23 2017

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

October 22 2021

Estimated Enrollment :

700 Patients enrolled

Trial Details

Trial ID

NCT03350139

Start Date

October 23 2017

End Date

October 22 2021

Last Update

November 22 2017

Active Locations (1)

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Assistance Publique Hôpitaux de Marseille

Marseille, France, 13354