Status:
COMPLETED
Insulin Schemes for Type 2 Diabetes Control
Lead Sponsor:
Universidad de Guanajuato
Conditions:
Type 2 Diabetes Mellitus
Eligibility:
All Genders
18-100 years
Phase:
PHASE4
Brief Summary
The aim of the study is to determine differences in glycemic control between a basal-bolus scheme insulin and NPH scheme insulin in a population of hospitalized patients with type 2 diabetes in a Nonc...
Detailed Description
On the first 4 to 6 h, the use of NPH insulin present a pronounced action peak on the postprandial glucose metabolism, and the rest of its basal action last 12 to 18 h, its cover the postprandial requ...
Eligibility Criteria
Inclusion
- Patients between 18 and 100 years old.
- History of type 2 diabetes mellitus (DM2) or that upon admission is diagnosed by values of glycated haemoglobin (HbA1) \> 6.5%
- Fasting central glucose before randomization between 140mg/dl and 400mg/dl
- Non-critical patients hospitalized in the service of Internal Medicine (MI), General Surgery (CG) and Traumatology (TyO).
- Patients receiving a diabetic diet orally
- Treated with diet alone, o any combination of oral anti-diabetic agents or insulin treatment with any dosage before admission.
Exclusion
- Parenteral nutrition
- Hyperglycemia without a known history of diabetes
- Impaired renal function (glomerular filtration rate less than 30)
- Diabetic ketoacidosis and hyperosmolar state
- Type 1 Diabetes mellitus
- Pregnancy
- Patients on treatment with more than 10mg prednisone or steroid boluses.
- Known hypopituitarism or adrenal insufficiency
- Hyperglycaemia due to stress (negative antecedent of DM2, hyperglycemia and HbA1 \<6.5)
- Severe liver disease (Child-Pugh C score)
- Acute pancreatitis
- Patients with sepsis or multiple organ failure
- Candidates for intensive care unit
Key Trial Info
Start Date :
November 2 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2018
Estimated Enrollment :
75 Patients enrolled
Trial Details
Trial ID
NCT03350984
Start Date
November 2 2017
End Date
July 1 2018
Last Update
December 6 2021
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Hospital General de León
León, Guanajuato, Mexico, 37680