Status:
COMPLETED
Effect of Microbial Exposure on Health, Particularly Immune System
Lead Sponsor:
University of Helsinki
Collaborating Sponsors:
Tampere University
Conditions:
Immune System Disorders
Eligibility:
All Genders
18-85 years
Phase:
PHASE1
Brief Summary
The effect of microbial exposure on healthy human subjects will be investigated. Changes in cytokine and IgE and vaccine response will be measured. The hypothesis is that microbial exposure increases ...
Detailed Description
The effect of microbial exposure on healthy human subjects will be investigated. The volunteers will either receive material containing a microbial inoculum, or they will receive nothing. Changes in c...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Healthy adults that live in urban conditions; that do not own a furry pet; that do not have HIV or other condition that weakens immune system; that do not use drugs chilling immune system; that do not have a history of five active infections that caused hospitalization within 2 years; that do not have a condition affecting immune response (e.g. rheumatoid, colitis ulcerosa, Crohn disease); that do not have dementia, acute depression or psychosis; that do not have cancer within 2 years; that do not have sore skin in arms or hands; that do not have diabetes; that do not have incompetency; that have not received earlier vaccine against Pneumococcus sp.; that do not have unwillingness to receive the vaccine; that do not live in countryside.
Exclusion
Key Trial Info
Start Date :
March 1 2016
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2017
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT03351543
Start Date
March 1 2016
End Date
July 1 2017
Last Update
November 24 2017
Active Locations (1)
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1
Helsinki University
Lahti, Kanta-Häme, Finland, 15140