Status:

COMPLETED

Zero Positive End-expiratory Pressure Before Emergence Prevents Postoperative Atelectasis.

Lead Sponsor:

Region Västmanland

Conditions:

Atelectasis

Oxygenation

Eligibility:

All Genders

40-75 years

Phase:

NA

Brief Summary

A study on healthy patients undergoing anesthesia for non-abdominal surgery - evaluation of positive end-expiratory pressure versus zero positive end-expiratory pressure on the amount of atelectasis i...

Detailed Description

Positive end-expiratory pressure (PEEP) is often used during mechanical ventilation to preserve end-expiratory lung volume. After emergence and extubation, this volume will diminish instantly. Some pa...

Eligibility Criteria

Inclusion

  • American Society of Anesthesiology (ASA) class I-II
  • Non-abdominal day case surgery under general anesthesia

Exclusion

  • Body mass index (BMI) ≥30 kg/m2
  • Arterial oxygen saturation (SpO2) breathing air \<95 %
  • Chronic Obstructive Pulmonary Disease (COPD) or symptomatic asthma
  • Symptomatic congestive heart failure
  • Ischemic heart disease
  • Hemoglobin \<100 g/L
  • Active smokers
  • Active smokers and ex-smokers with a history of more than 6 pack years.
  • Need for interscalene or supraclavicular plexus block for postoperative pain relief (risk of phrenic nerve paralysis).

Key Trial Info

Start Date :

December 4 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 28 2018

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT03351946

Start Date

December 4 2017

End Date

August 28 2018

Last Update

September 5 2018

Active Locations (1)

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1

Department of Anaesthesia and Intensive Care

Köping, Sweden