Status:
COMPLETED
IMRT vs 2DRT for NPC Patients
Lead Sponsor:
Chinese University of Hong Kong
Conditions:
NPC
Eligibility:
All Genders
Brief Summary
Irradiation of the parotid gland with subsequent long-term xerostomia is a well-recognized complication after radiotherapy for head and neck (HAN) cancers. A number of studies have shown that IMRT cou...
Eligibility Criteria
Inclusion
- The NPC patient, who had been enrolled, randomized and treated in the prior prospective randomized study of IMRT vs 2DRT.
- Regular follow-up for more than five years from the end of study intervention (i.e. IMRT or 2DRT for NPC).
- Patient is able to sign the study-specific informed consent.
- ECOG performance status 0 or 1.
- Patient is able to complete the study's questionnaire.
Exclusion
- NPC patients who had not been randomized or allocated to the study intervention, even though had been enrolled in the prior reported study.
- Loss of regular follow-up from the end of study intervention.
- Regular follow-up for less than five years from the end of study intervention.
- Patients with known recurrent or metastatic disease.
- Patients with secondary malignancy occurred after completion of the previous study's treatment (i.e. radiotherapy).
- Active untreated infections
- Major medical or psychiatric illness
Key Trial Info
Start Date :
November 29 2017
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 30 2021
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT03352778
Start Date
November 29 2017
End Date
June 30 2021
Last Update
October 22 2021
Active Locations (1)
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1
The Chinese University of Hong Kong
Hong Kong, Hong Kong