Status:

UNKNOWN

Substudy of CADRE: for People With Extreme Phenotype: BIOCADRE

Lead Sponsor:

Cardiologie et Développement

Collaborating Sponsors:

Institut National de la Santé Et de la Recherche Médicale, France

Conditions:

Sickle Cell Disease

Eligibility:

All Genders

10+ years

Brief Summary

BIOCADRE is a CADRE substudy and aims to characterize more precisely the sickle cell patients with extreme phenotype.

Detailed Description

Sickle cell disease (SCD) is the most frequent monogenic disease in the world, due to a unique mutation on the β-globin gene. Most affected individuals live in sub-Saharan Africa, yet, the natural his...

Eligibility Criteria

Inclusion

  • sickle cell patients with extreme phenotypes: SS-hemoglobin

Exclusion

  • transfusion in the previous 2 months
  • vaso-occlusive crisis in the previous 15 days
  • infection in the previous 8 days

Key Trial Info

Start Date :

May 15 2017

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2019

Estimated Enrollment :

300 Patients enrolled

Trial Details

Trial ID

NCT03352986

Start Date

May 15 2017

End Date

December 1 2019

Last Update

November 24 2017

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Centre de Recherches er de Lutte contre la Drépanocytose

Bamako, Mali

2

Centre National de Transfusion Sanguine

Dakar, Senegal