Status:

RECRUITING

Effect of Virtual Reality Technology for Pain Management of Vaso-Occlusive Crisis in Patients With Sickle Cell Disease

Lead Sponsor:

St. Jude Children's Research Hospital

Conditions:

Sickle Cell Disease

Vaso-occlusive Crisis

Eligibility:

All Genders

6-25 years

Phase:

NA

Brief Summary

Acute vaso-occlusive crisis (VOC) is the most common complication in patients with sickle cell disease (SCD) and pain related to VOC is often inadequately treated. This is a phase II randomized contro...

Detailed Description

After consenting to participate in this study, patients will be randomized to receive either standard care therapy for VOC or to receive standard care therapy plus a 15-minute virtual reality (VR) ses...

Eligibility Criteria

Inclusion

  • Participant must have sickle cell disease (any genotype), documented in the St. Jude medical record.
  • Participant must be seeking care for acute VOC pain at St. Jude Children's Research Hospital.
  • Participant age must be ≥ 6 years and ≤ 25 years.
  • English speaking

Exclusion

  • Prior randomization in this study.
  • Patients are currently enrolled on another pain management interventional trial for the presenting pain crisis.
  • Mild pain (score \<4), or pain for which treatment with opioid is not indicated.
  • Pain in combination with other clinical symptoms that require additional interventions, including fever with focus, acute chest syndrome, acute injury, or splenic sequestration.
  • Developmental or psychiatric disorders like autism, claustrophobia or other disabilities like vision and hearing defects etc. that preclude the use of a head mounted device.
  • Inability or unwillingness of research participant or legal guardian/ representative to give written informed consent.

Key Trial Info

Start Date :

February 5 2018

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

November 1 2026

Estimated Enrollment :

76 Patients enrolled

Trial Details

Trial ID

NCT03353584

Start Date

February 5 2018

End Date

November 1 2026

Last Update

September 18 2025

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Methodist Comprehensive Sickle Cell Center

Memphis, Tennessee, United States, 38104

2

St. Jude Children's Research Hospital

Memphis, Tennessee, United States, 38105