Status:
COMPLETED
The Effect of Statin Treatment on Trained Innate Immunity
Lead Sponsor:
Radboud University Medical Center
Collaborating Sponsors:
AIDS Malignancy Consortium
Erasmus Medical Center
Conditions:
Atherosclerosis
Eligibility:
All Genders
18+ years
Brief Summary
The innate immune system plays a pivotal role in the development and progression of atherosclerosis. Recently, it was reported that monocytes can develop a long-lasting immunological memory after stim...
Detailed Description
The innate immune system plays a pivotal role in the development and progression of atherosclerosis. Recently, it was reported that monocytes can develop a long-lasting immunological memory after stim...
Eligibility Criteria
Inclusion
- Aged 18 years or older
- Elevated LDL levels (\>4.9 mmol/l)
- Decision made by treating physician to initiate statin treatment
Exclusion
- previous cardiovascular events.
Key Trial Info
Start Date :
January 1 2015
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2016
Estimated Enrollment :
45 Patients enrolled
Trial Details
Trial ID
NCT03354156
Start Date
January 1 2015
End Date
December 1 2016
Last Update
November 27 2017
Active Locations (1)
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1
Radboud university medical center
Nijmegen, Netherlands, 6500 GA