Status:
COMPLETED
Cortical Neuroplasticity by Muscle Pain of Pain-induced Plasticity
Lead Sponsor:
Aalborg University
Conditions:
Nerve Growth Factor
Exercise
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
The purpose of this study is to investigate the sensory-motor cortical excitability response to delayed onset muscle soreness (DOMS) on Extensor Carpi Radialis (ECR) muscle during muscle hyperalgesia ...
Detailed Description
The purpose of this study is to assess changes in sensory-motor cortical excitability during experimental muscle hyperalgesia across several days provoked by injections of nerve growth factor (NGF) in...
Eligibility Criteria
Inclusion
- Healthy men and women
- Speak and understand English.
Exclusion
- Pregnancy
- Drug addiction defined as the use of cannabis, opioids or other drugs
- Previous neurologic, musculoskeletal or mental illnesses
- Lack of ability to cooperate
- History of chronic pain or current acute pain
- Previous experience with rTMS
- Contraindications to rTMS application (history of epilepsy, metal in the head or jaw etc.).
- Failure to pass the "TASS questionnaire" (TASS = Transcranial Magnetic Stimulation Adult Safety Screen)
Key Trial Info
Start Date :
November 26 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 28 2018
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT03354624
Start Date
November 26 2017
End Date
February 28 2018
Last Update
March 5 2018
Active Locations (1)
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1
Aalborg University
Aalborg, North Denmark, Denmark, 9000