Status:

RECRUITING

Genetic Susceptibility to Listeriosis

Lead Sponsor:

Institut Pasteur

Collaborating Sponsors:

Icahn School of Medicine at Mount Sinai

Conditions:

Listeriosis

Eligibility:

All Genders

Phase:

NA

Brief Summary

Listeriosis is a rare, severe foodborne infection, responsible for severe invasive infections. It occurs in the great majority of cases in elderly patients and / or patients with comorbidities, with a...

Detailed Description

Listeriosis is a rare, severe foodborne infection caused by the bacterium Listeria monocytogenes (Lm), responsible for severe invasive infections. It occurs in the great majority of cases in elderly p...

Eligibility Criteria

Inclusion

  • Inclusion Criteria for patients with Listeriosis :
  • Microbiologically documented Listeriosis (either a severe form of listeriosis, or an atypical form of listeriosis, or less than 40 years old and without any co-morbidity identified)
  • Affiliated or beneficiary of a social security system
  • Informed and written consent
  • Inclusion Criteria for volunteers related to patients with Listeriosis (after identifying a genetic susceptibility in the patient with Listeriosis) :
  • defined as father, mother, brother (s), sister (s), child (ren), grandparent (s), uncle (s), aunt (s), cousin (s), nephew (s), niece (s).
  • Affiliated or beneficiary of a social security system
  • Informed and written consent
  • Exclusion Criteria for volunteers related to patients with Listeriosis:
  • Inability to consent

Exclusion

    Key Trial Info

    Start Date :

    November 28 2017

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    November 30 2027

    Estimated Enrollment :

    100 Patients enrolled

    Trial Details

    Trial ID

    NCT03357536

    Start Date

    November 28 2017

    End Date

    November 30 2027

    Last Update

    September 19 2025

    Active Locations (1)

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    Page 1 of 1 (1 locations)

    1

    Centre Médical de l'Institut Pasteur

    Paris, France, 75015