Status:

COMPLETED

LOD Before IVF/ICSI in PCOS Patients With High AMH

Lead Sponsor:

Mansoura University

Conditions:

Infertility

Polycystic Ovarian Syndrome

Eligibility:

FEMALE

18-35 years

Brief Summary

To evaluate the effect of performing laparoscopic ovarian drilling (LOD) before proceeding to in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) on the cycle outcomes in polycysti...

Detailed Description

Retrospective case-control study of PCOS women with high serum AMH level (≥ 7 ng/ml) who were subjected IVF/ICSI. Women underwent LOD in the preceding 3 months prior to IVF/ICSI (study group) will be ...

Eligibility Criteria

Inclusion

  • PCOS women subjected to COS through fixed gonadotropin releasing hormone (GnRH) antagonist protocol with final triggering of oocyte maturation by GnRH agonist (GnRHa)
  • Elevated serum AMH level (≥ 7 ng/ml)

Exclusion

  • Age \< 18 years or \> 35 years
  • Body mass index (BMI) \< 19 kg/m2 or \> 35 kg/m2
  • Use of cabergoline therapy or coasting to minimize the risk of OHSS

Key Trial Info

Start Date :

March 22 2013

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 18 2017

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT03358199

Start Date

March 22 2013

End Date

June 18 2017

Last Update

December 2 2017

Active Locations (1)

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Fertility Care Unit (FCU) in Mansoura University Hospital

Al Mansurah, Dakahlia Governorate, Egypt, 35111