Status:
NOT_YET_RECRUITING
Radiotherapy vs Neck Dissection for Clinical T1/2N0 Supraglottic Cancer
Lead Sponsor:
Tianjin Medical University Cancer Institute and Hospital
Collaborating Sponsors:
Tianjin Medical University General Hospital
Tianjin Medical University Second Hospital
Conditions:
Supraglottic Cancer
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
Supraglottic cancer is a main type of laryngeal carcinoma, which is one of the most common head and neck tumors. Cervical nodal metastasis is an important prognostic factor in supraglottic cancer. Cur...
Eligibility Criteria
Inclusion
- Ability to understand and the willingness to sign a written informed consent document
- Age≥ 18 and≤ 75 years
- Histological/ cytological/ Imaging examination proven supraglottic squamous-cell carcinoma in preoperative assessment
- Cervical node negative according to the imaging characteristics and the physical examination
- KPS≥ 70
- Normal bone marrow reserve function and normal liver, kidney function
- Expected survival period≥ 12 months
Exclusion
- Inability to provide an informed consent
- Proved distant metastasis
- Clinical stage 3-4
- The patient has received prior surgery or radiotherapy (except for biopsy )
- The patient has received chemotherapy(including targeted therapies) or immunotherapy
- Prior malignancy within the previous 5 years
- Severe mental disorders
- Pregnant or lactating women
- Other disease requiring simultaneous surgery or radiotherapy
- Researchers believe that the situation is unsuitable for participation in the group
Key Trial Info
Start Date :
December 20 2017
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 1 2027
Estimated Enrollment :
158 Patients enrolled
Trial Details
Trial ID
NCT03358602
Start Date
December 20 2017
End Date
November 1 2027
Last Update
December 12 2017
Active Locations (1)
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1
Tianjin Medical University Cancer Institute and Hopital
Tianjin, Tianjin Municipality, China, 300000