Status:
COMPLETED
Brown Adipose Tissue Activation: Effect of Exercise Training and Irisin
Lead Sponsor:
Turku University Hospital
Conditions:
Physical Activity
Eligibility:
MALE
18-45 years
Phase:
NA
Brief Summary
This study investigates the brown adipose tissue (BAT) activation and metabolism using positron emission tomography (PET) imaging before and after exercise training intervention at fasting state under...
Detailed Description
Exercise training has been suggested to activate and recruit human BAT through the activation of sympathetic nervous system and contracting skeletal muscles by the release of myokines such as lactate ...
Eligibility Criteria
Inclusion
- Healthy sedentary volunteer
- BMI 20-25 kg/m2
- Age: 18-45 years
- No chronic diseases
Exclusion
- BMI \< 20 kg/m2 or BMI \> 25 kg/m2
- Mental disorder or poor compliance
- Eating disorder or excessive use of alcohol or tobacco smoking
- Any chronic disease
- Past dose of radiation
- Presence of any ferromagnetic objects that would make MR imaging contraindicated
- Physically disability which rule out the physical fitness tests or participation in the exercise training intervention
- Any other condition that in the opinion of the investigator could create a hazard to the subject safety, endanger the study procedures or interfere with the interpretation of study results
Key Trial Info
Start Date :
September 17 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 27 2015
Estimated Enrollment :
11 Patients enrolled
Trial Details
Trial ID
NCT03359824
Start Date
September 17 2013
End Date
May 27 2015
Last Update
January 22 2019
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