Status:
COMPLETED
OSA-ACS Project: Association of OSA and CPAP Therapy With Outcomes in ACS Patients
Lead Sponsor:
Beijing Anzhen Hospital
Conditions:
Obstructive Sleep Apnea of Adult
Acute Coronary Syndrome
Eligibility:
All Genders
18+ years
Brief Summary
Obstructive sleep apnea (OSA) is an increasingly common chronic disorder in adults that has been strongly associated with various forms of cardiovascular disease. Compared to the general population, O...
Eligibility Criteria
Inclusion
- Age ≥18 years old
- Admission with an ACS (including STEMI, NSTEMI, and unstable angina)
- Written informed consent
Exclusion
- Cardiogenic shock (systolic blood pressure \<90mmHg)
- Cardiac arrest on admission or during hospitalization
- Severe insomnia, chronic sleep deprivation, abnormal circadian rhythm (sleep duration \<4h/night)
- Predominantly central sleep apnea (CSA, ≥50% central events or central apnea hypopnea index (AHI) ≥10/h)
- Previous or current use of CPAP
- Known or planned pregnancy
- Severe comorbidities: eg. malignancy (life expectancy \<2 years)
- Patients who cannot tolerate the sleep study or refuse it
Key Trial Info
Start Date :
May 1 2015
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2020
Estimated Enrollment :
2160 Patients enrolled
Trial Details
Trial ID
NCT03362385
Start Date
May 1 2015
End Date
December 1 2020
Last Update
September 5 2021
Active Locations (1)
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1
Beijing Anzhen Hospital, Capital Medical University
Beijing, China, 100029