Status:
COMPLETED
The Effect of Prednisone on Atherogenesis as Studied in the Macrophage Foam Cell Formation Model System.
Lead Sponsor:
Prof. Tony hayek MD
Conditions:
Atherosclerosis
Dyslipidemias
Eligibility:
MALE
18-50 years
Phase:
EARLY_PHASE1
Brief Summary
Glucocorticoids (GCs) are a class of endogenous steroid hormones produced by the adrenal glands and controlled by the hypothalamic-pituitary-adrenal axis (HPA). One of the mechanisms of their action i...
Eligibility Criteria
Inclusion
- Male subjects between the ages of 18-50 years of age, with a body mass index within the range of 18 to 27 kg/m2, with no previous medical history of illnesses or drug allergy and with no current medical treatments.
Exclusion
- Students or hospital employees under the direct supervision of the PI or lead researcher. Any previous history of acute or chronic illnesses including but not limited to Cardiovascular, Pulmonary, Gastrointestinal, Renal, Endocrinal, Cancer, Diabetes or Pre-Diabetes (HbA1c \> 5.5%), Hypertension, Dyslipidemia, Smoking, or who had taken glucocorticoids within the previous 3 months before the study.
Key Trial Info
Start Date :
January 17 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 30 2018
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT03367663
Start Date
January 17 2018
End Date
September 30 2018
Last Update
February 21 2019
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Rambam Health Care Campus
Haifa, Israel, 31096