Status:
NOT_YET_RECRUITING
Neck Dissection vs Radiotherapy for Cervical Metastases in Advanced Hypopharyngeal Cancer
Lead Sponsor:
Tianjin Medical University Cancer Institute and Hospital
Collaborating Sponsors:
Tianjin Medical University Second Hospital
Tianjin Medical University General Hospital
Conditions:
Hypopharyngeal Carcinoma
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
At the time of diagnosis, approximately 60%-80% of patients with hypopharyngeal cancer are found with cervical lymph node metastasis. Cervical nodal metastasis is an important prognostic factor in hyp...
Eligibility Criteria
Inclusion
- Ability to understand and the willingness to sign a written informed consent document
- Age≥ 18 and≤ 75 years
- Histological/ cytological/ Imaging examination proven hypopharyngeal squamous-cell carcinoma in preoperative assessment
- Advanced hypopharyngeal cancer with metastatic cervical lymph node more than 2cm in diameter
- EPOG≤1,KPS≥ 70
- No contraindication of surgery and radiotherapy
- No serious disease history of the heart, liver, kidney, lung and other important organs
- Expected survival period≥ 12 months
- Good compliance
Exclusion
- Inability to provide an informed consent
- Other malignancy tumor history,(except for cured skin basal cell carcinoma and papillary thyroid carcinoma)
- Serious cardiovascular, liver, respiratory, kidney and neurologic and psychiatric disease with clinical symptoms
- The patient has received prior surgery or radiotherapy (except for biopsy)
- The patient has received chemotherapy or immunotherapy
- Pregnant or lactating women
- Other disease requiring simultaneous surgery or radiotherapy
Key Trial Info
Start Date :
January 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2028
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT03367884
Start Date
January 1 2018
End Date
January 1 2028
Last Update
December 12 2017
Active Locations (1)
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1
Tianjin Medical University Cancer Institute and Hospital
Tianjin, Tianjin Municipality, China, 300000