Status:
COMPLETED
Exercise Effects on Word Learning
Lead Sponsor:
VA Office of Research and Development
Conditions:
Aging
Aphasia
Eligibility:
All Genders
35-89 years
Phase:
NA
Brief Summary
The aging Veteran population will substantially increase over the next 10 years, as the 24.9% of Veterans who are currently between 55-64 years of age join the 38.5% who are already over age 65. The r...
Detailed Description
Difficulty retrieving the right word to communicate a message is the most common complaint in healthy older adults and individuals with stroke-induced language impairment (i.e., aphasia). Novel word l...
Eligibility Criteria
Inclusion
- monolingual English speakers
- "low physical activity" on the International Physical Activity Questionnaire
- physician's written approval for participation in moderate-intensity exercise
Exclusion
- VO2 max \>26 (men) and 22 (women)
- inability to cycle for 3 minutes at 50 revolutions/minute with no resistance
- any comorbid condition with exercise contraindications
- use of hormone replacement therapy
- dopaminergic
- anti-depressant
- anti-psychotic
- or illicit drugs
- consumption of \>14 alcoholic drinks/week or \> 1pack of cigarettes/day
- uncorrected hearing or vision impairments that interfere with study procedures
- inability to read or repeat nonwords (e.g., flark)
- inability to learn one novel word during a practice learning task
- below cut-off on the Montreal Cognitive Assessment or the Comprehensive Aphasia Test Cognitive Screen
- and/or \>10 on the Beck Depression Inventory
Key Trial Info
Start Date :
December 9 2016
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 16 2019
Estimated Enrollment :
28 Patients enrolled
Trial Details
Trial ID
NCT03370471
Start Date
December 9 2016
End Date
August 16 2019
Last Update
September 5 2021
Active Locations (1)
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1
Atlanta VA Medical and Rehab Center, Decatur, GA
Decatur, Georgia, United States, 30033