Status:
COMPLETED
Acute Neuroimmune Effects of Alcohol Using Free Water Imaging
Lead Sponsor:
Brown University
Collaborating Sponsors:
National Institute of General Medical Sciences (NIGMS)
Conditions:
Alcohol Drinking
Eligibility:
All Genders
21-45 years
Phase:
NA
Brief Summary
This study examines the effects of moderate alcohol intake on the brain, the immune system, and cognition.
Detailed Description
The study involves a within-subjects, pre/post design to assess the effects of a moderate dose of alcohol on immune biomarkers, neurobiological measures, and cognitive functioning. The study recruits ...
Eligibility Criteria
Inclusion
- Ages 21-45 years
- Able to speak and read English at least at 8th grade level
- Moderate self-reported alcohol use in the past year
- Body mass index in normal to overweight range
- Right-handed
Exclusion
- History of heavy drinking
- Currently seeking alcohol or drug treatment
- Chronic disease requiring use of medication
- Recent antibiotic or probiotic use
- Chronic daily use of NSAIDs
- Chronic GI disorder
- Use of illicit drugs
- Major psychiatric disorder or suicidality
- Fainting, weakness, infection, excessive bruising, or distress resulting from standard blood draw
- Safety contraindication for MRI scan
- Inability to abstain from use of tobacco products prior to or during study
- Inability to abstain from use of cannabis prior to or during study
- Pregnant, nursing, or may become pregnant
Key Trial Info
Start Date :
March 31 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 28 2017
Estimated Enrollment :
25 Patients enrolled
Trial Details
Trial ID
NCT03370783
Start Date
March 31 2017
End Date
September 28 2017
Last Update
July 20 2022
Active Locations (1)
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1
Brown University
Providence, Rhode Island, United States, 02912