Status:
UNKNOWN
The Effect of Glucocorticoid Therapy on Left Ventricular Remodelling in Acute Myocardial Infarction (RECONSIDER)
Lead Sponsor:
Iuliu Hatieganu University of Medicine and Pharmacy
Collaborating Sponsors:
Romanian Governmental Funding (UEFISCDI)
Conditions:
ST-segment Elevation Myocardial Infarction
Left Ventricular Remodeling
Eligibility:
All Genders
18-85 years
Phase:
PHASE2
PHASE3
Brief Summary
Introduction: In the setting of acute ST-segment elevation myocardial infarction (STEMI) coronary wedge pressure (CWP) emerges as a new marker for the advanced form of pre-procedural microvascular obs...
Detailed Description
PATIENT POPULATION Consecutive patients with first STEMI, candidates for PPCI (typical cardiac chest pain, within 12h of symptom onset, with ST segment elevation of more than 1 mm in at least two cont...
Eligibility Criteria
Inclusion
- age: 18-85 years
- first episode of ST-segment elevation myocardial infarction
- candidates for primary PCI (typical cardiac chest pain, within 12h of symptom onset, with ST-segment elevation of more than 1 mm in at least two contiguous leads)
- left anterior descending artery culprit lesion
Exclusion
- cardiogenic shock
- previous PCI and coronary artery bypass surgery (CABG)
- left bundle branch block
- active bleeding
- administration of thrombolytic agents for the current episode
- recent stroke (during last month)
- indication for oral anticoagulant therapy
- severe or untreated infection
- the impossibility of CWP measurement.
Key Trial Info
Start Date :
March 8 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2020
Estimated Enrollment :
77 Patients enrolled
Trial Details
Trial ID
NCT03371784
Start Date
March 8 2018
End Date
December 1 2020
Last Update
September 28 2020
Active Locations (1)
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1
"Niculae Stancioiu" Heart Institute
Cluj-Napoca, Cluj, Romania, 400001