Status:

COMPLETED

Corticosteroid Lumbar Epidural Analgesia for Radiculopathy

Lead Sponsor:

Scilex Pharmaceuticals, Inc.

Collaborating Sponsors:

Worldwide Clinical Trials

Semnur Pharmaceuticals, Inc.

Conditions:

Lumbosacral Radicular Pain

Eligibility:

All Genders

18-70 years

Phase:

PHASE3

Brief Summary

This is a research study of SP-102, an experimental medication designed to relieve pain in patients with a specific type of leg pain. The medication is given once by your healthcare professional, with...

Eligibility Criteria

Inclusion

  • Main
  • Able and willing to read, write, and understand the English language and provide English language written informed consent prior to beginning any study procedures.
  • Age 18 to 70 years (inclusive) at the Screening Visit.
  • A diagnosis of lumbosacral radicular pain (sciatica).
  • Agrees to follow study-specific medication requirements.
  • If sexually active and a female of child-bearing potential or a male capable of bearing a child, agrees to use an effective method of birth control during the study.
  • Has reviewed all study specific materials and has, in the opinion of the Investigator, the abilities to understand and appropriately complete all study procedures.
  • Main

Exclusion

  • Has radiologic evidence of a condition that would compromise study outcomes.
  • Has ever had lumbosacral back surgery or plans to undergo spine surgical intervention while in the study.
  • Has been diagnosed with insulin dependent diabetes mellitus.
  • Presence of any other disorder, condition or circumstance (including secondary gain) that, in the opinion of the Investigator, has the potential to prevent study completion and/or to have a confounding effect on outcome assessments.
  • Use of any investigational drug and/or device within 30 days, or is scheduled to receive an investigational drug other than blinded study drug during this study.
  • Has a body mass index ≥40 kg/m2.

Key Trial Info

Start Date :

December 8 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 6 2022

Estimated Enrollment :

401 Patients enrolled

Trial Details

Trial ID

NCT03372161

Start Date

December 8 2017

End Date

January 6 2022

Last Update

September 19 2022

Active Locations (37)

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Page 1 of 10 (37 locations)

1

Semnur Research Site 75

Mobile, Alabama, United States, 36605

2

Semnur Research Site 52

Phoenix, Arizona, United States, 85053

3

Semnur Research Site 58

Tempe, Arizona, United States, 85284

4

Semnur Research Site 18

La Jolla, California, United States, 92037