Status:
RECRUITING
Tau PET in Imaging and Cognition: Healthy Adults From 55-90
Lead Sponsor:
Yaakov Stern
Collaborating Sponsors:
National Institute on Aging (NIA)
Conditions:
Mild Cognitive Impairment
Aging
Eligibility:
All Genders
55-90 years
Brief Summary
The investigators aim to use the new PET radioligand, 18F-MK-6240, to detect tau pathology in cognitive healthy and mild cognitive impairment (MCI) elders. The investigators will then examine the inte...
Detailed Description
Many cognitively healthy older adults have, upon post mortem evaluations, been found to have varying amounts of neurofibrillary tangles (tau) and beta-amyloid plaque deposits, which are the hallmark b...
Eligibility Criteria
Inclusion
- Aged 55-90
- Previously received an amyloid PET scan
- Residing near Columbia University Medical Center
- Must be willing and able to participate
Exclusion
- Have a contraindication to PET (e.g, metallic implants, pacemaker, claustrophobia, or cannot lie flat for one hour)
- Pregnancy
- Lactating Women
- Current, past, or anticipated exposure to radiation
- Significant active physical illness
Key Trial Info
Start Date :
June 1 2018
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2027
Estimated Enrollment :
105 Patients enrolled
Trial Details
Trial ID
NCT03372317
Start Date
June 1 2018
End Date
December 1 2027
Last Update
February 5 2025
Active Locations (1)
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1
Columbia University Medical Center
New York, New York, United States, 10032