Status:
COMPLETED
Cuff Leak Test and Airway Obstruction in Mechanically Ventilated ICU
Lead Sponsor:
McMaster University
Conditions:
Laryngeal Edema
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Introduction: Endotracheal intubation and mechanical ventilation are lifesaving interventions that are commonly done in the intensive care unit (ICU). The act of intubating someone can cause laryngeal...
Detailed Description
INTRODUCTION Endotracheal intubation and mechanical ventilation are lifesaving interventions. However, as with acute interventions, can be associated with serious complications. One such complication ...
Eligibility Criteria
Inclusion
- Eligible patients will be mechanically ventilated adults (\>18 years) who are admitted to the ICU and an order to extubate has been provided by the treating physician.
Exclusion
- A palliative care, a one-way extubation, or a decision to withdraw advances life support order has been written.
- Pregnancy.
- Patients at high risk for LE: burn patients, smoke inhalation injuries (as defined as singed facial hair or nasal hair, carbonaceous secretions/sputum, and known to be in an enclosed fire), blunt or penetrating trauma involving the neck and airway, postoperative head and neck surgeries, and patients admitted with airway edema to the ICU (e.g; anaphylaxis).
- Patients with either a difficult or traumatic endotracheal intubation.
- Patients receiving mechanical ventilation via tracheostomy.
- Known preexisting tracheolaryngeal abnormalities such as: vocal cord paralysis, tracheolaryngeal neoplasm, tracheomalacia, tracheolaryngeal stenosis, or previous head and neck surgeries.
- Patients receiving systemic corticosteroids of greater than 30 mg of PO prednisone or equivalent, within 4 days prior to the decision to extubate.
- Patients who failed extubation attempt within the current ICU admission.
- History of postextubation airway obstruction.
- The ICU physician declined enrolling the patient.
- Patient had a failed CLT in the previous 24 hours.
Key Trial Info
Start Date :
July 5 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2019
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT03372707
Start Date
July 5 2018
End Date
July 1 2019
Last Update
August 26 2022
Active Locations (3)
Enter a location and click search to find clinical trials sorted by distance.
1
St Joseph's Hospital
Hamilton, Ontartio, Canada, L8N 46
2
Jagiellonian University Medical College
Krakow, Lesser Poland Voivodeship, Poland, 31-066
3
Imam Adbulrahman Bin Faisal University
Dammam, Eastern Province, Saudi Arabia, 34212