Status:
RECRUITING
Gut Microbiota of Preterm Infants and Full-term Infants at Early Life
Lead Sponsor:
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Conditions:
Preterm Infant
Gut Microbiome
Eligibility:
All Genders
1-4 years
Brief Summary
The aim of this study is to obtain a longitudinal view of the gut microbial establishment of a cohort of 51 preterm (PT) infants compared to 50 full-term (FT) infants from birth to 90 days of age, and...
Detailed Description
Premature birth is a global clinical problem. Early colonization and development of the neonatal gut microbiome is critically important with a profound impact on the host lifelong health. V3-V4 region...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Preterm infants
- gestational age \<37 weeks;
- no gastrointestinal tract disorders, metabolic diseases, or viral hepatitis;
- hospital stay \> 7 days;
- Exclusion criteria:
- NICU stay less than 7 days
- Necrotizing enterocolitis infant
- Control group:
- Full-term healthy infants;
- gestational age \>37 weeks;
- vaginally born;
- no gastrointestinal tract disorders, metabolic diseases, or viral hepatitis.
Exclusion
Key Trial Info
Start Date :
July 20 2014
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 20 2028
Estimated Enrollment :
102 Patients enrolled
Trial Details
Trial ID
NCT03373721
Start Date
July 20 2014
End Date
December 20 2028
Last Update
April 17 2024
Active Locations (1)
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1
Department of NICU, XinHua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Shanghai, China