Status:

COMPLETED

The Effect of Pseudoexfoliation on Choroidal Thickness in Open Angle Glaucoma

Lead Sponsor:

Emine Deniz Egrilmez

Collaborating Sponsors:

Izmir Ataturk Training and Research Hospital

Conditions:

Glaucoma, Open-Angle

Eligibility:

All Genders

18+ years

Brief Summary

Purpose: To investigate the effect of pseudoexfoliation (PEX) on choroidal thickness in primary open-angle glaucoma (POAG). Methods: This prospective, randomized study included 30 POAG patients and 3...

Detailed Description

In the present study, the investigators aimed to evaluate the effect of the presence of PEX on choroidal thickness in two groups of glaucoma patients with similar degrees of damage and similar demogra...

Eligibility Criteria

Inclusion

  • The study included subjects over 18 years old who had best corrected visual acuity of 0.5 or better, transparent optic medium, at least two reliable visual field tests, and reliable spectral domain (SD)-OCT (signal strength≥7/10) and EDI-OCT images (signal strength≥6/10)

Exclusion

  • Information pertaining to patients' systemic diseases and chronic medication use was recorded. Patients with diabetes mellitus, systemic arterial hypertension, renal failure, hemodialysis history, chronic medication, or smoking habit were not included.
  • Patients with retinal and neuro-ophthalmological diseases, amblyopia, active or previous uveitis, previous ocular trauma, intraocular surgery within last 6 months, previous trabeculectomy, or refractive error with a spherical equivalent greater than ±3.0 D were excluded from the study. In order to minimize the effect of IOP on choroidal thickness, patients with IOP higher than 21 mmHg at the time of OCT image acquisition were not included in the study.

Key Trial Info

Start Date :

August 15 2014

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

August 15 2015

Estimated Enrollment :

90 Patients enrolled

Trial Details

Trial ID

NCT03373942

Start Date

August 15 2014

End Date

August 15 2015

Last Update

December 18 2017

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