Status:

COMPLETED

Effect Of Intravenous IntralipidTherapyon Pregnancy Outcome in Women With History of Recurrent Implantation Failure Undergoing Intracytoplasmic Sperm Injection-Embryo Transfer Cycle: A Randomized Controlled Trial

Lead Sponsor:

King Fahad Medical City

Conditions:

Infertility Due to Nonimplantation

Eligibility:

FEMALE

21-42 years

Phase:

PHASE2

Brief Summary

To evaluate the effect ofempiricintralipidinfusion therapy on pregnancy outcomes in patient withunexplained recurrentimplantation failure (RIF) undergoIntracytoplasmic sperm injection (ICSI).

Detailed Description

the aim to evaluate the effect ofempiricintralipidinfusion therapy on pregnancy outcomes in patient withunexplained recurrentimplantation failure (RIF) undergoIntracytoplasmic sperm injection (ICSI). ...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • age \< 42 years
  • BMI \< 30 kg/m2
  • history of 3 or more recurrent implantation failure undergoing Intracytoplasmic Sperm Injection (ICSI ) cycle.
  • exclusion criteria
  • women with medical contraindications of intralipidinfusion.
  • uterine fibroid.
  • endometrial polyp.
  • endometriosis,hydrosalpinx.
  • intrauterine adhesion and uterine anomalies.
  • Women with positive thrombophilia screen.
  • diminished ovarian reserve.
  • severe male factor infertility .
  • chronic medical illnesses which may contribute in impaired chance of pregnancy .

Exclusion

    Key Trial Info

    Start Date :

    January 1 2015

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    June 30 2017

    Estimated Enrollment :

    142 Patients enrolled

    Trial Details

    Trial ID

    NCT03374163

    Start Date

    January 1 2015

    End Date

    June 30 2017

    Last Update

    December 15 2017

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