Status:
COMPLETED
Volumetric Intensity Modulated Arc Therapy vs. Conventional Radiotherapy for Cancer Pain
Lead Sponsor:
Centre hospitalier de l'Université de Montréal (CHUM)
Conditions:
Neoplasm Metastasis
Pain
Eligibility:
All Genders
Phase:
NA
Brief Summary
This study compares the use of conventional radiotherapy technique with volumetric intensity-modulated radiotherapy (VMAT) in the treatment of painful cancer metastases. Half of the patients will rece...
Detailed Description
Radiotherapy to painful sites of metastasis can provide pain relief. Side-effects from radiotherapy is dependent on the volume and dose received by normal tissues. Conventional radiotherapy technique...
Eligibility Criteria
Inclusion
- Pain (SF-BPI score ≥1) should be related to metastases (bone or others) or to the tumor itself
- Capable of providing the full list of analgesic medication being used
- Capable of completing the SF-BPI and EORTC questionnaires without any help
- Life expectancy of at least 3 month
- KPS greater or equal to 50
- Radiotherapy to 1 site pain
- Site of treatment not previously irradiated
- No planned changes in analgesic within 7 days before and after treatment
- • Patient may be started on Dexamethasone on the first day of radiotherapy
- No planned chemotherapy, radiotherapy or surgery within 7 days before and after treatment
- Patient provided informed consent to participate in this study
Exclusion
- Major mental or psychiatric impairments, which in the investigator's opinion will prevent administration or completion of the protocol therapy and/or interfere with follow-up.
- Treatment to upper and lower limb
- Treatment to 2 or more sites of pain
- Re-irradiation of the site of treatment
- Women who are pregnant
- Life expectancy less than 3 month
Key Trial Info
Start Date :
July 7 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 21 2018
Estimated Enrollment :
73 Patients enrolled
Trial Details
Trial ID
NCT03374592
Start Date
July 7 2014
End Date
February 21 2018
Last Update
November 16 2022
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