Status:
COMPLETED
Neutrophil Extracellular Traps in Systemic Sclerosis
Lead Sponsor:
CHU de Reims
Conditions:
Systemic Lupus Erythematosus
Systemic Sclerosis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Systemic sclerosis (SSC) is a systemic disease characterized by limited or diffuse cutaneous sclerosis, microangiopathy, overproduction of autoantibodies and variable organ damage due to vasculopathy ...
Detailed Description
This study is designed to assess the role of neutrophil extracellular traps (NETs) in systemic sclerosis as well as to evaluate the correlation between NETs production and NETs composition and the dif...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- for patients of arm 1:
- patients with systemic lupus erythematosus
- patients consenting to participate to the study
- patients enrolled in the national healthcare insurance program
- for patients of arm 2:
- patients with systemic sclerosis
- patients consenting to participate to the study
- patients enrolled in the national healthcare insurance program
- For patients of arm 3 (healthy volunteers)
- Patients without Chronic inflammatory systemic disease
- Patients without Current or past neoplasy,
- patients without chronic metabolic pathology
- patients without treatment by anti inflammatory or corticotherapy for the last 15 days,
- patients without infectious pathology or inflammatory acute for the last 15 days
Exclusion
Key Trial Info
Start Date :
February 23 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 29 2021
Estimated Enrollment :
81 Patients enrolled
Trial Details
Trial ID
NCT03374618
Start Date
February 23 2018
End Date
April 29 2021
Last Update
June 13 2024
Active Locations (1)
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1
Damien JOLLY
Reims, France