Status:
COMPLETED
Opioid Withdrawal Symptoms in Critically Ill Patients
Lead Sponsor:
Mahidol University
Conditions:
Substance Withdrawal Syndrome
Critical Illness
Eligibility:
All Genders
Brief Summary
Most critically ill patients encounter pain and distress from acute illness, medical procedures and devices as well as routine care in the intensive care units (ICU). Opioids are principal analgesics ...
Detailed Description
The primary objective of the study is to explore incidence of OWS in adult critically ill patients. The secondary objectives are 1) to identify factor associated OWS, 2) establish the assessment tool ...
Eligibility Criteria
Inclusion
- Age ≥18 years
- On mechanical ventilator at least 24 hours
- Received continuous infusion of opioid at least 24 hours
- Patient or legal surrogate who is willing and able to provide written informed consent and comply with all protocol requirements
Exclusion
- Severely disturbed behavior pattern on account of underlying neurological disease (status epilepticus, encephalopathy, head trauma, brain injury, spinal cord injury)
- Preexisting psychiatric diagnosis
- Substance abuse prior to ICU admission
- Chronic alcohol drinking
- Pregnancy
- End-of-life care
- Death during ICU admission or during opioid IV infusion
Key Trial Info
Start Date :
January 1 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 7 2018
Estimated Enrollment :
55 Patients enrolled
Trial Details
Trial ID
NCT03374722
Start Date
January 1 2018
End Date
October 7 2018
Last Update
October 9 2018
Active Locations (1)
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1
Faculty of Pharmacy, Mahidol University
Ratchathewi, Bangkok, Thailand, 10400