Status:
COMPLETED
Dexmedetomidine Versus Propofol for Sedation in Stereotactic Brain Biopsy
Lead Sponsor:
Ain Shams University
Conditions:
Adverse Effects in the Therapeutic Use of Other and Unspecified Agents Primarily Acting on the Respiratory System
Eligibility:
All Genders
20-60 years
Phase:
PHASE4
Brief Summary
Pre-operative anxiety leads to higher sympathetic stimulation. Propofol in the main drug used during interventional or imaging techniques that need sedation. Also, dexmedetomidine causes sedation, ana...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Patients with:
- brain secondaries from the lung/breast/pancreas
- tuberculoma
- pyogenic abscess
- intra-axial supratentorial space occupying lesion with or without hydrocephalus \*an average duration of the procedure 1- 2hr 30 min
- an available caregiver for overnight observation
- patient relative proximity to the hospital Exclusion criteria
- Patients with:
- morbid obesity (body mass index \>35 kg/m2)
- significant comorbidities (a known history of hepatic disease, renal dysfunction, hypertension, and chronic pain)
- history of drug or alcohol abuse
- an allergic reaction to one of the study medications
- anticipated difficult airway
- uncontrolled epilepsy
- poor neurological status
- neuropsychological unsuitability taking psychotropic drugs (benzodiazepines and barbiturates)
- patients with brain stem lesions (vital areas of brain)
- un-cooperative
- refusing adults
- patients with ventricular drain
- already inpatient
- Intubated patients and those who had a prior craniotomy .
Exclusion
Key Trial Info
Start Date :
September 1 2016
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2017
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT03375385
Start Date
September 1 2016
End Date
December 1 2017
Last Update
April 1 2022
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.