Status:
COMPLETED
Application of n-3 Fatty to Patient of Jaundice
Lead Sponsor:
Huazhong University of Science and Technology
Conditions:
Obstructive Jaundice
Surgical Procedure, Unspecified
Eligibility:
All Genders
18-75 years
Brief Summary
The safety and efficacy of ω-3 fatty acid in patients with obstructive jaundice is not known. This study provided evidences that ω-3 fatty acid-based parenteral nutrition improved postoperative recove...
Detailed Description
Lipid emulsion enriched in n-3 fatty acid (FA) has been reported to improve postoperative recovery for surgical patients with biliary tract disease, and to improve laboratory and clinical outcomes. Th...
Eligibility Criteria
Inclusion
- the diagnosis of obstructive jaundice must be clear (serum toal bilirubin \>51.3umol/L \& Imaging evidence), and the obstruction is located in the extrahepatic bile duct;
- Duration of Jaundice is less than 2 weeks;
- Nutritional support is needed
- Nutritional support was administrated during the perioperative period;
- Drainage treatment is effective.
Exclusion
- Contraindication for surgical procedure, including Child-Pugh Classification C, severe hemorrhagic disorders, gastrointestinal hemorrhage, acute infectious disease, active phase of chronic hepatitis B \& C, severe circulatory disease, renal failure pre -operation, and other unknown cause;
- Abandon treatment;
- Length of stay in hospital \<5 day;
- Nutrition support \<5 day;
- Conservative treatment;
- Incomplete data;
- Allergic reactions against PN.
Key Trial Info
Start Date :
January 1 2014
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 15 2017
Estimated Enrollment :
106 Patients enrolled
Trial Details
Trial ID
NCT03376945
Start Date
January 1 2014
End Date
October 15 2017
Last Update
December 19 2017
Active Locations (1)
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1
Hepatic Surgery Center of Tongji Hospital
Wuhan, Hubei, China, 430030