Status:

ACTIVE_NOT_RECRUITING

Breast Cancer Screening: Digital Breast Tomosynthesis Versus Digital 2D Mammography

Lead Sponsor:

University Hospital Muenster

Collaborating Sponsors:

German Research Foundation

Conditions:

Breast Cancer Screening

Eligibility:

FEMALE

50-69 years

Phase:

NA

Brief Summary

This study is a randomized, multicenter, multivendor, controlled, diagnostic superiority trial to compare digital breast tomosynthesis plus synthesized 2D mammograms (DBT+s2D) versus standard 2D full-...

Detailed Description

The primary objective of the study is to evaluate whether digital breast tomosynthesis plus synthesized 2D mammograms leads to a relevant increase in the detection rate of screening-detected invasive ...

Eligibility Criteria

Inclusion

  • Women eligible to participate in the National Mammography Screening Program of Germany
  • Informed decision for mammography screening
  • Written informed consent
  • No prior participation in the TOSYMA trial

Exclusion

  • Breast cancer up to 5 years prior to study invitation
  • Previous mammography examination \< 12 months,
  • Breast implants

Key Trial Info

Start Date :

July 5 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 31 2026

Estimated Enrollment :

99689 Patients enrolled

Trial Details

Trial ID

NCT03377036

Start Date

July 5 2018

End Date

March 31 2026

Last Update

December 2 2024

Active Locations (21)

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Page 1 of 6 (21 locations)

1

Screening-Einheit Hannover; Mammographie-Einheit Hannover

Hanover, Lower Saxony, Germany, 30449

2

Screening-Einheit Niedersachsen Nordost; Mammographie-Einheit Lüneburg

Lüneburg, Lower Saxony, Germany, 21337

3

Screening-Einheit Niedersachsen Nord; Mammographie-Einheit Stade

Stade, Lower Saxony, Germany, 21680

4

Screening-Einheit Niedersachsen Mitte; Mammographie-Einheit Vechta

Vechta, Lower Saxony, Germany, 49377