Status:

UNKNOWN

The Association Between Platelet Reactivity and Bleeding Risk in Adult ITP

Lead Sponsor:

Shandong University

Collaborating Sponsors:

Traditional Chinese Medicine Hospital Affiliated to Shandong University

Jinan Central Hospital

Conditions:

Immune Thrombocytopenia

Eligibility:

All Genders

18-80 years

Brief Summary

It seems reasonable to assume that patients who present significant bleeding symptoms may have different quality of platelets than those without bleeding. This question was addressed in a study that e...

Detailed Description

The investigators are undertaking a prospective multicenter double-blind study of 400 adult patients with immune thrombocytopenia from 6 medical centers in China. We adopted three different assays tha...

Eligibility Criteria

Inclusion

  • Untreated adult ITP patients of both genders between the ages of 18 and 80 years.
  • Participants of either acute or chronic phase; with or without thrombocytopenia; with or without bleeding manifestation.

Exclusion

  • Received high-dose steroids or IVIG within 3 weeks prior to the test.
  • Received second-line ITP-specific treatments (eg, cyclophosphamide, 6-mercaptopurine, vincristine, vinblastine, etc) within 3 months prior to the test.
  • Current HIV infection, hepatitis B virus or hepatitis C virus infections.
  • Severe medical condition (liver and kidney function impairment).

Key Trial Info

Start Date :

December 1 2017

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2018

Estimated Enrollment :

400 Patients enrolled

Trial Details

Trial ID

NCT03377439

Start Date

December 1 2017

End Date

December 1 2018

Last Update

December 19 2017

Active Locations (1)

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Qilu Hospital, Shandong University

Jinan, Shandong, China, 250012