Status:
UNKNOWN
The Effects Probiotic Has on Gastromicroecology and Combined With Quadruple Regimen for H Pylori Infection
Lead Sponsor:
Yiqi Du
Conditions:
Efficacy
Gastric Microbiota
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
This study assesses the efficacy and safety of treatment with two-week probiotics followed by a 10-day tetracycline- and furazolidone-containing quadruple regimen as rescue treatment for H. pylori inf...
Detailed Description
Currently the infection rate of H. pylori is high. H. pylori infection has a close relationship with human diseases , Among the patients with H. pylori infection, 100% have active gastritis, \<10% sho...
Eligibility Criteria
Inclusion
- All included patients were 18 to 70 years-old; negative for the urea breath test at least 4 weeks after last eradication treatment; and experienced at least 2 H. pylori eradication failures.
Exclusion
- Patients were excluded if they presented with a severe comorbidity or a malignant tumor; had a known history of allergy to the drugs in the therapeutic regimen; used nonsteroidal anti-inflammatory drugs (NSAIDs), antibiotic therapy, or bismuth salts up to 4 weeks before study inclusion; or were pregnant or breast-feeding.
Key Trial Info
Start Date :
March 15 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 15 2020
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT03377933
Start Date
March 15 2019
End Date
March 15 2020
Last Update
June 24 2019
Active Locations (1)
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1
Changhai hospital
Shanghai, China