Status:
COMPLETED
Task-dependent Operation of a Mechanism Intracortical Inhibition in Dystonia
Lead Sponsor:
University Hospital, Lille
Conditions:
Dystonia, Primary
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
Cortical excitability depends on inhibitory mechanisms efficiency among which long latency intracortical inhibition (LICI) can be studied by paired pulses transcranial magnetic stimulation (TMS). Some...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Patient with hand dystonia : writers cramp
- Subject affiliated to social security regimen.
- For healthy volunteers :
- Healthy volunteer without neurological disorders based on sensorimotor examination.
- Subject affiliated to social security regimen.
- Exclusion Criteria :
- Subject unable to receive informed consent (dementia).
- Contraindication to Transcranial Magnetic Stimulation(TMS) (epilepsia, intracranial metalic foreign object, hearing device, cochlear implant).
- Patient using a psychotrope treatment.
- Patient under guardianship or curatorship.
- Pregnant or nursing women.
- Patient with a cardiac stimulator.
- For healthy volunteers only :
- • Abnormal neurological evaluation based on sensorimotor examination or neurological history ( epilepsy, stroke ; brain or spinal cord surgery ; history of neurological disease affective sensitive and motor control)
Exclusion
Key Trial Info
Start Date :
April 1 2015
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2017
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT03381456
Start Date
April 1 2015
End Date
April 1 2017
Last Update
December 22 2017
Active Locations (1)
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1
Hôpital Roger Salengro, CHRU de Lille
Lille, France