Status:
COMPLETED
Diode Laser for Treatment of Peri-implantitis
Lead Sponsor:
University of Geneva, Switzerland
Conditions:
Peri-Implantitis
Implant Complication
Eligibility:
All Genders
Phase:
NA
Brief Summary
The primary objective is to evaluate the clinical and patient-centered outcomes of non-surgical mechanical debridement with adjunctive repeated diode laser application (test) in comparison with conven...
Detailed Description
Peri-implantitis is a major complication for dental implant patients, with its prevalence estimated in the order of 10% of implants and 20% of patients after 5 to 10 years of implant placement. When l...
Eligibility Criteria
Inclusion
- Informed Consent as documented by signature (Appendix Informed Consent Form)
- At least one solid screw-type titanium implant diagnosed with peri-implantitis; which is defined as at least one site with probing depth ≥5mm, bleeding on probing and/or suppuration, and radiographic evidence of crater-form bone loss ≥2 threads after insertion of the final prosthetic supra-structure.
- Sound prosthetic supra-structure.
Exclusion
- Contraindications to the class of drugs under study, e.g. known hypersensitivity or allergy to Amoxicillin and/or Metronidazole,
- Systemic diseases that could compromise wound healing (i.e. uncontrolled diabetes mellitus, cancer, HIV or bone metabolic disorders), radiation or immunosuppressive therapy,
- Women who are pregnant or breast feeding,
- Known or suspected non-compliance, drug or alcohol abuse,
- Heavy smokers consuming \>10 cigarettes/day,
- Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc. of the participant,
- Participants not willing to attend regular dental maintenance visits and follow-up evaluations,
- Participation in another study with investigational drug within the 30 days preceding and during the present study,
- Previous enrolment into the current study,
- Active periodontal disease.
Key Trial Info
Start Date :
October 10 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 30 2021
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT03383120
Start Date
October 10 2017
End Date
April 30 2021
Last Update
May 4 2021
Active Locations (1)
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1
University of Geneva
Geneva, Genève 4, Switzerland, 1211